Item: Super Bandage
Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
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Summons a big attack fly that can be controlled with the shooting direction-keys.
Grants a reward if all enemies in a room are killed in the order they are marked.
Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.
Adds a chance to fire a gas cloud that damages nearby enemies.
A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.
Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.
Tears shrink and do much less damage, but fire in very rapid succession.
Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).
Makes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased . If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.
Spawns a finger familiar that points at enemies, dealing constant damage.
Key Piece 2
Combined with Key Piece 1, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan.
Connects Isaac's tears with electricity that can damage enemies.
An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.