Item: Sworn Protector

Replaces tears with a piercing laser with unlimited range.

Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Fliesdamaging enemies it passes through.

Chaos causes items to be chosen from random item pools. When picked up, drops between 1-6 random pickups on the floor.

Zodiac will give Isaac a random zodiac item effect that changes after every floor.

Removed in Afterbirth: Automatically inflicts slow to all enemies in every room.
Added in Afterbirth: Upon taking damage, inflicts slow to all enemies for the current room.

Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.

Increases Damage by 1.

Increases damage by 1 and range by 5 for tears fired from the left eye.

Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy.

Grants 7 bombs and allows bombs to be placed rapidly.

Spawns a familiar that follows Isaac around and fires tears with random effects.

This item turns all doors that require a key into doors which need a coin to enter instead. This affects shops, item rooms, libraries and other key doors.

Adds 3 heart containers.

Taking damage releases a ring of 10 high damage tears.

Adds a chance to shoot fear tears and decreases tear delay by 1.

Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider.

Upon picking up a certain amount of health, spawn a permanent angelic familiar.

Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears.

Isaac can hold 2 pills at once and all cards are replaced by pills.

Spider enemies no longer target or deal contact damage to Isaac.