Item: The Mulligan

Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.

Causes Isaac's activated item to activate twice on each use.

Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider.

Connects Isaac's tears with electricity that can damage enemies.

Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.

Two items spawn in every Treasure Room. Only one can be taken; the other will disappear.

Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny.

Grants four soul hearts and fully restores Isaac's red health.

+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room.

Grants flight and increases speed.

Grants a soul heart. Adds a chance to block enemy shots.

Grants two empty heart containers and heals Isaac by half a heart, but decreases speed by 0.2.

Gives Isaac 5 bombs, and makes Isaac's bombs have a chance to drop random pickups or charm enemies when they explode.

Grants spectral tears and flight.

Increases damage by 1, range by 5.25, and tear height by 0.5.

A familiar that damages enemies by chasing them as well as inducing the fear effect.

Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.

Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.

Spawns a familiar that slowly charges forward and damages enemies in its path.

A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.