Item: The Small Rock
Spawns allied blue spiders from killed enemies.
Activated Items can be "overcharged" to allow for an additional use.
Follows Isaac and automatically fires at enemies in its reach.
A familiar that follows Isaac around shooting blood tears.
Range up and makes shot tears revolve around Isaac until they drop.
Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections.
Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Whore of Babylon
Increases damage and speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any soul or black hearts.
Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard?pill. Isaac's tears also travel above all obstacles.
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Gives one heart container and doubles the healing provided by red hearts.
+1.7 tears, +0.3 speed, reduces damage.
Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.
A demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects.