Item: The Soul
When Isaac is hit, 1 point of an item's charge is filled.
Spawns a familiar that flies the room while firing, dealing double Isaac's tear damage to enemies that come in contact and retrieving pickups.
While firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle.
Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
Activated Items can be "overcharged" to allow for an additional use.
Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.
Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
Summons a familiar that copies the tears of Isaac's other familiars.
Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Grants 1 heart container and increases tears, but decreases shot speed.
Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
Spawns a cloud familiar that leaves a trail of tears that damages enemies. Has a chance to spawn damaging beams of light onto enemies that touch the cloud.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
Reveals and opens all Secret Room and Super Secret Room entrances.
After every 15 tears fired, Isaac will fire a high-damage cluster of tears.
Reveals all rooms for every floor. However, it does not reveal icons or secret rooms.
Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
Increases Damage and Speed, plus adds one Soul Heart.